Key Characteristics
- Category: Injectable Peptides
- Purity: >99% Purity
- Molecular Formula: C39H65N5O7
- Molecular Weight: 767.9 g/mol
- Sequence: Hexanoyl-Tyr-Ile-Ahx-NH2
Available Sizes
About
Dihexa is a synthetic peptide researched for its potent nootropic (cognitive-enhancing) properties. It is highly stable, orally active, and readily crosses the blood-brain barrier to enhance synaptogenesis and promote neural regeneration.
Mechanism of Action
Dihexa's primary mechanism involves its potent binding to and activation of Hepatocyte Growth Factor (HGF) and its receptor, c-Met. This activation stimulates the growth of new dendrites and synapses (synaptogenesis), which is believed to be the basis for its powerful effects on memory, learning, and neural repair.
Key Benefits
- Potent nootropic effects
- Enhances synaptogenesis and neural connections
- Neuroprotective properties
- May improve memory and learning
Clinical Research
In vitro studies have shown Dihexa to be seven orders of magnitude more potent than Brain-Derived Neurotrophic Factor (BDNF) in promoting new synapse formation. In animal models of Alzheimer's, Dihexa was able to reverse cognitive deficits.
Potential Side Effects
Research on Dihexa is still ongoing, but current studies have not highlighted significant adverse side effects. As it is a potent growth factor activator, long-term effects are a subject of continued investigation.
Usage & Dosage
Due to its high potency, research dosages are typically very small, often in the microgram range. It can be administered subcutaneously or topically in a DMSO solution for transdermal research.
Peptide Storage
Best Practices For Storing Peptides
To preserve the integrity of laboratory results, proper storage of peptides is essential. Correct storage practices can maintain peptides for years and guard against contamination, oxidation, and degradation. If the peptides will be used immediately, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks.
For longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). Avoid repeated freeze-thaw cycles and do not use frost-free freezers, as temperatures can fluctuate widely.
Preventing Contamination
To prevent moisture contamination, allow the peptide to come to room temperature before opening its container. Minimize exposure to air; after use, reseal the container under an atmosphere of dry, inert gas (like nitrogen or argon) if possible. Peptides with Cys, Met, or Trp are especially prone to air oxidation.
Storing Peptides In Solution
The shelf life of peptide solutions is far less than that of lyophilized peptides. If peptides must be stored in solution, use sterile buffers at pH 5-6 and separate into aliquots to avoid repeated freezing and thawing. Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F).